Discovery of chromosomal integrons from metagenomic sequences

• This website collects computational tools that we developed for integron gene cassettee identification in metagenomic sequences; and genes we predicted from the Human Microbiome Project (HMP) datasets.
• Ref: Yu-Wei Wu, Mina Rho, Thomas G. Doak and Yuzhen Ye. Oral spirochetes implicated in dental diseases are widespread in normal human subjects and carry extremely diverse integron gene cassettes. Appl. Environ. Microbiol. August 2012 vol. 78 no. 15 5288-5296 (go to paper)
• Download the software | README
  
• A file with sequences of the 8 representative attC sites from the Treponema denticola genome
  
• Predicted integron genes from the HMP datasets: amino acid sequences | nucleotide acid sequences
  
• Contacts: Yu-Wei Wu (yuwwu@indiana.edu) and Yuzhen Ye (yye@indiana.edu)